段恒
【摘要】 目的:探討蝶骨嵴腦膜瘤術(shù)后遲發(fā)性顱內(nèi)血腫的臨床治療與預(yù)后情況。方法:本次研究選取陽(yáng)新縣人民醫(yī)院2015年2月-2018年2月收治32例蝶骨嵴腦膜瘤術(shù)后遲發(fā)性顱內(nèi)血腫患者,對(duì)相關(guān)資料進(jìn)行回顧性分析,患者均行開顱血腫清除術(shù),觀察其術(shù)后療效、治療滿意度情況,并監(jiān)測(cè)兩組患者并發(fā)癥發(fā)生率及轉(zhuǎn)歸情況。結(jié)果:32例患者均順利完成開顱血腫清除術(shù),術(shù)后予以高壓氧干預(yù),肌力恢復(fù)良好。療效評(píng)估顯示總有效率為90.63%(29/32),治療滿意度為87.50%(28/32),開顱血腫清除術(shù)后并發(fā)癥發(fā)生率為18.75%(6/32),開顱血腫清除術(shù)后患者均未見(jiàn)繼發(fā)性顱內(nèi)血腫形成、術(shù)后癲癇、遺留神經(jīng)功能缺損等嚴(yán)重并發(fā)癥,預(yù)后良好。結(jié)論:蝶骨嵴腦膜瘤術(shù)后遲發(fā)性顱內(nèi)血腫及時(shí)行開顱血腫清除術(shù),可有效清除血腫,改善癥狀,療效可靠,預(yù)后良好,但需注意做好并發(fā)癥監(jiān)測(cè),及時(shí)處理與治療。
【關(guān)鍵詞】 蝶骨嵴腦膜瘤術(shù) 遲發(fā)性顱內(nèi)血腫 臨床研究
doi:10.14033/j.cnki.cfmr.2020.08.052??文獻(xiàn)標(biāo)識(shí)碼 B??文章編號(hào) 1674-6805(2020)08-0-02
Clinical Study of Delayed Intracranial Hematoma in 32 Patients with Sphenoid Ridge Meningioma/DUAN Heng. //Chinese and Foreign Medical Research, 2020, 18(8): -125
[Abstract] Objective: To investigate the clinical treatment and prognosis of delayed intracranial hematoma after sphenoid ridge meningioma operation. Method: In this study, 32 patients with delayed intracranial hematoma after sphenoid ridge meningioma operation were treated in Yangxin County Peoples Hospital from February 2015 to February 2018. The relevant data were analyzed retrospectively. All patients underwent craniotomy for hematoma removal, and their postoperative efficacy and treatment satisfaction were observed, and the incidence and outcome of complications were monitored. Result: All the 32 patients successfully completed the removal of hematoma after craniotomy. After the operation, hyperbaric oxygen intervention was given and the muscle strength recovered well. The results showed that the total effective rate was 90.63% (29/32), the satisfaction rate was 87.50% (28/32), the complication rate was 18.75% (6/32). There were no serious complications such as secondary intracranial hematoma, postoperative epilepsy, left neurological deficit and so on in all the patients after craniotomy. Conclusion: The delayed intracranial hematoma after sphenoid ridge meningioma operation can be removed effectively, the symptoms can be improved, the curative effect is reliable, the prognosis is good, but we should pay attention to the complications monitoring, timely treatment and treatment.
[Key words] Sphenoid ridge meningioma Delayed intracranial hematoma Clinical study
First-authors address: Yangxin County Peoples Hospital, Yangxin 435200, China
蝶骨嵴腦膜瘤(orbitosphenoid meningioma)是腦膜瘤的一種類型,占腦膜瘤總數(shù)的13%~19%,是臨床常見(jiàn)的顱底板腦膜瘤類型[1-2]。手術(shù)切除是治療蝶骨嵴腦膜瘤的主要方法,但是開顱手術(shù)可引起局部血管、組織損傷,同時(shí)全身麻醉也可引起血壓波動(dòng)等情況,因而患者術(shù)后易出現(xiàn)顱內(nèi)血腫形成等并發(fā)癥,其中術(shù)后遲發(fā)性顱內(nèi)血腫較為常見(jiàn),目前對(duì)于其治療與預(yù)后研究逐漸增多[3-5]。術(shù)后遲發(fā)性顱內(nèi)血腫的病情進(jìn)展較快,可迅速引起神經(jīng)功能異常、腦疝、腦衰竭等不良預(yù)后,多數(shù)患者需立即實(shí)施開顱血腫清除術(shù)[6]。為進(jìn)一步探明蝶骨嵴腦膜瘤術(shù)后遲發(fā)性顱內(nèi)血腫的臨床治療與預(yù)后情況,本次研究選取本院32例蝶骨嵴腦膜瘤術(shù)患者術(shù)后遲發(fā)性顱內(nèi)血腫問(wèn)題進(jìn)行分析,對(duì)患者開顱血腫清除術(shù)的效果進(jìn)行了分析,并追蹤觀察了患者術(shù)后并發(fā)癥情況,現(xiàn)將相關(guān)病例報(bào)道如下。
[2] Nordenskjld A C,Bujila R,Aspelin P,et al.頭顱CT檢查后腦膜瘤的患病風(fēng)險(xiǎn)[J].國(guó)際醫(yī)學(xué)放射學(xué)雜志,2018,41(1):96.
[3]羅藝,季學(xué)兵.多排螺旋CT血管成像在腦膜瘤術(shù)前評(píng)估中的應(yīng)用[J].立體定向和功能性神經(jīng)外科雜志,2017,30(5):284-288.
[4]張杰,高晉健,張德明,等.外科治療以癲癇為主要癥狀的腦膜瘤124例[J].實(shí)用醫(yī)學(xué)雜志,2018,34(3):427-430,449.
[5]楊俊,賴杰,羅云平,等.術(shù)前頭部CT血管造影在腦膜瘤治療中的應(yīng)用[J].廣西醫(yī)學(xué),2018,40(13):1431-1433.
[6] Yogendranathan N,Herath H M M T B,Pahalagamage S P,et al.
Electrocardiographic changes mimicking acute coronary syndrome in a large intracranial tumour:A diagnostic dilemma[J].Bmc Cardiovascular Disorders,2017,17(1):91.
[7]方謙昊,朱紅,何瀚志,等.基于卷積神經(jīng)網(wǎng)絡(luò)的腦膜瘤亞型影像自動(dòng)分級(jí)[J].南京師大學(xué)報(bào):自然科學(xué)版,2018,41(3):22-27.
[8]何亞文,梁亞明,盧偉坤,等.術(shù)前栓塞術(shù)對(duì)24例腦膜瘤的療效評(píng)價(jià)[J].中國(guó)醫(yī)藥科學(xué),2016,6(24):201-203.
[9] Huang Y,Wang Z,Han Q.Extracranial-intracranial bypass in medial sphenoid ridge meningioma associated with severe stenosis of the intracranial segments of the internal carotid artery:A case report[J].Medicine,2018,97(24):e11123.
[10]陳健龍,于沛濤.淺析間變性腦膜瘤的治療及預(yù)后[J].醫(yī)學(xué)與哲學(xué)(B),2017,38(6):55-57.
[11] Ho W S,Sizdahkhani S,Hao S,et al.LB-100, a novel protein Phosphatase 2A (PP2A) inhibitor,sensitizes malignant meningioma cells to the therapeutic effects of radiation[J].Cancer Letters,2017,415:217-226.
[12]吳勝波,魏婷婷,趙軍,等.術(shù)前栓塞輔助治療腦膜瘤效果Meta分析[J].人民軍醫(yī),2017,60(10):979-983.
[13]楊俊,莫鴻忠,賴杰,等.雙源CTA在蝶骨嵴腦膜瘤術(shù)前檢查的應(yīng)用價(jià)值[J].腦與神經(jīng)疾病雜志,2016,24(10):638-642.
(收稿日期:2019-11-20) (本文編輯:何玉勤)
①陽(yáng)新縣人民醫(yī)院 湖北 陽(yáng)新 435200