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      酉時(shí)中藥燙熨治療老年性骨質(zhì)疏松癥的療效分析

      2019-08-19 03:38:22夏一嬌
      中外醫(yī)療 2019年14期
      關(guān)鍵詞:骨質(zhì)疏松癥

      夏一嬌

      [摘要] 目的 分析酉時(shí)中藥燙熨治療老年性骨質(zhì)疏松癥的療效。 方法 便利選取2016年6月— 2018年8月在遼寧中醫(yī)藥大學(xué)附屬醫(yī)院骨K2科住院的100例老年性骨質(zhì)疏松癥患者。按隨機(jī)數(shù)字表,將他們平均分為對(duì)照組與治療組。對(duì)照組只給予鈣爾奇 D3片及骨化三醇膠丸口服治療,治療組在對(duì)照組治療的基礎(chǔ)上于酉時(shí)行中藥(熟地,細(xì)辛,白芍,杜仲,續(xù)斷,金狗脊,牛膝)燙熨患部。觀察兩組患者骨密度值、相關(guān)生化指標(biāo)、疼痛評(píng)分、療效及功能改善情況。 結(jié)果 治療組骨密度值[腰椎(0.84±0.05)g/m2,髖部(0.85±0.04)g/m2],明顯高于對(duì)照組[腰椎骨密度(0.76±0.01)g/m2,髖部骨密度(0.78±0.03)g/m2(P<0.05),治療組堿性磷酸酶指標(biāo)下降(t=5.441,P<0.05),治療組VAS 評(píng)分(2.25±0.64)分,顯著低于對(duì)照組(5.32±0.85)分(t=8.364,P<0.05),Oswestry指數(shù)治療組(60.21±5.74)分顯著低于對(duì)照組(71.35±5.54)分(P<0.05)。 結(jié)論 酉時(shí)中藥燙熨能有效增加骨密度、調(diào)節(jié)鈣磷代謝,減輕骨痛,改善功能活動(dòng)障礙。

      [關(guān)鍵詞] 骨質(zhì)疏松癥;酉時(shí);中藥燙熨

      [中圖分類號(hào)] R259? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-0742(2019)05(b)-0150-04

      [Abstract] Objective To analyze the efficacy of traditional Chinese medicine ironing in the treatment of senile osteoporosis. Methods From June 2016 to August 2018, Convenient select 100 cases of senile osteoporosis were admitted to the K2 department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. They were divided into a control group and a treatment group by random number table. In the control group, only Calcium D3 tablets and calcitriol capsules were given orally. The treatment group was treated with traditional Chinese medicine on the basis of the control group (rehmannia, asarum, white peony, eucommia ulmoides, continuation, golden dog ridge, achyranthes) ironing the affected area. The bone mineral density, related biochemical indicators, pain score, efficacy and functional improvement were observed in the two groups. Results The bone mineral density of the treatment group [lumbar vertebrae (0.84±0.05)g/m2, hip bone mineral density was (0.85±0.04)g/m2] was significantly higher than the control group [lumbar vertebrae density (0.76±0.01)g/m2, hip bone mineral density was (0.78±0.03)g/m2] (P<0.05), and the alkaline phosphatase index of the treatment group decreased (t=5.441, P<0.05). VAS score of the treatment group (2.25±0.64)points was significantly lower than the control group(5.32±0.85)points(t=8.364, P<0.05), and the Oswestry index treatment group (60.21±5.74)points was significantly lower than the control group (71.35±5.54)points (P<0.05). Conclusion Chinese herbal medicine can effectively increase bone density, regulate calcium and phosphorus metabolism, reduce bone pain and improve functional activity disorder.

      [Key words] Osteoporosis; Sputum; Chinese medicine ironing

      我國是人口老齡化大國,以髖關(guān)節(jié)為例,每年由于重度骨質(zhì)疏松癥導(dǎo)致髖關(guān)節(jié)骨折的患者有近20萬人以上,骨質(zhì)疏松癥已成為危害老年人生存質(zhì)量的重癥之一[1-3],該病主要的臨床表現(xiàn)為廣泛性的骨痛、乏力、稍有不慎即可發(fā)生脆性骨折。該文旨在分析2016年6月— 2018年8月在中醫(yī)藥理論指導(dǎo)下酉時(shí)中藥燙熨對(duì)100例老年性骨質(zhì)疏松癥患者的治療作用。報(bào)道如下。

      該研究兩組患者治療后骨密度都顯著增加。治療組[腰椎骨密度0.84±0.05)g/m2,髖部骨密度(0.85±0.04g/m2],明顯高于對(duì)照組[腰椎骨密度(0.76±0.01g/m2,髖部骨密度(0.78±0.03)g/m2,堿性磷酸酶均有所降低。治療組堿性磷酸酶(53.21±4.1)U/L]顯著降低,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。兩組患者血肌酐、血鈣都有所下降,治療組血肌酐、血鈣差異無統(tǒng)計(jì)學(xué)意義(P>0.05),說明血鈣降低則堿性磷酸酶降低,堿性磷酸酶作為骨轉(zhuǎn)換生化標(biāo)記物,可以顯著抑制破骨細(xì)胞的骨吸收。疼痛方面,治療組VAS 評(píng)分(2.25±0.64)分顯著低于對(duì)照組(5.32±0.85)分(P<0.05),Oswestry指數(shù)治療組(60.21±5.74分)顯著低于對(duì)照組(71.35±5.54)分(P<0.05)。有研究對(duì)78例老年骨質(zhì)疏松患者采用中藥薰蒸結(jié)合密蓋息肌內(nèi)注射,取得了94.9%的總有效率,較該研究低1.1%。相關(guān)學(xué)者等對(duì)46例原發(fā)性骨質(zhì)疏松患者采用中藥熏洗治療,取得了87%的總有效率,VAS評(píng)分改善為(1.2±0.4)分??傆行瘦^該研究低9%,VAS評(píng)分較該研究高了大約1分。說明該方法能明顯減輕患者疼痛,改善功能障礙。綜上,酉時(shí)中藥燙熨治療老年性骨質(zhì)疏松癥療效肯定,且操作安全,經(jīng)濟(jì)實(shí)惠,值得臨床推廣使用。

      [參考文獻(xiàn)]

      [1]? Wang L,Hu YQ,Zhao ZJ,et al.Screening and validation of serum protein biomarkers for early postmenopausal osteoporosis diagnosis[J].Mol Med Rep,2017,16(6):8427-8433.

      [2]? García - Gomáriz C,Blasco JM,Macián - Romero C,et al.Effect of 2 years of endurance and high - impact training on preventing osteoporosis in postmenopausal women:randomized clinical trial[J].Menopause,2018,25(3): 301-306.

      [3]? Moradi S,Khorrami - Nezhad L,Maghbooli Z,et al.Vitamin D receptor gene variation,dietary intake and bone mineral density in obese women: a cross sectional study[J].J Nutr Sci

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