• <tr id="yyy80"></tr>
  • <sup id="yyy80"></sup>
  • <tfoot id="yyy80"><noscript id="yyy80"></noscript></tfoot>
  • 99热精品在线国产_美女午夜性视频免费_国产精品国产高清国产av_av欧美777_自拍偷自拍亚洲精品老妇_亚洲熟女精品中文字幕_www日本黄色视频网_国产精品野战在线观看 ?

    Refractive outcomes after vitrectomy combined with phacoemulsification of idiopathic macular holes

    2021-02-03 09:27:02BoShiLiuWeiNaCuiRuiNiuQiongChenZeTongNieJiaoTingWeiBoJieHu

    Bo-Shi Liu, Wei-Na Cui, Rui Niu, Qiong Chen, Ze-Tong Nie, Jiao-Ting Wei, Bo-Jie Hu

    Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Ⅰnternational Joint Research and Development Centre of Ophthalmology and Vision Science, Eye Ⅰnstitute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China

    Abstract

    ● AlM: To report the refractive outcomes after vitrectomy combined with phacoemulsification and intraocular lens (IOL) implantation (phaco-vitrectomy) in idiopathic macular holes (IMH).

    ● METHODS: A total of 56 eyes with IMH (IMH group) that underwent phaco-vitrectomy and 44 eyes with age-related cataract (ARC group) that underwent cataract surgery were retrospectively reviewed. The best corrective visual acuity (BCVA), predicted refractive error (PRE), actual refractive error (ARE), axial length (AL), were measured in both groups before and 6mo after operation. The power calculation of IOL and the predicted refractive error (PRE) were calculated according to the SRK/T formula. The difference of PRE and ARE between the two groups were compared and analyzed.

    ● RESULTS: In the IMH group, the diameters of macular holes were 271.73±75.85 μm, the closure rate was 100%. The pre- and post-operative BCVA were 0.80±0.35 and 0.40±0.35 logMAR. The PRE of A-ultrasound and IOL Master in the IMH group was -0.27±0.25 and 0.10±0.66 D. The postoperative mean absolute prediction error (MAE) was observed to be 0.58±0.65 and 0.53±0.37 D in the IOL Master and A-ultrasound (P=0.758). The PRE and ARE of the IMH group were 0.10±0.66 D and -0.19±0.64 D (P=0.102). The PRE and ARE of the ARC group was -0.43±0.95 and -0.31±0.93 D (P=0.383). The difference between PRE and ARE was -0.33±0.81 and 0.09±0.64 D in the IMH and ARC groups (P=0.021). The proportion of myopic shift was 67.9% in the IMH group and 27.3% in the ARC group (P=0.004).

    ● CONCLUSlON: The myopic shift can be observed in patients with IMH after phaco-vitrectomy.

    ● KEYWORDS: idiopathic macular hole; vitrectomy; phacoemulsification; intraocular lens implantation; refractive error; myopic shift

    INTRODUCTION

    Ⅰdiopathic macular hole (ⅠMH) predominantly affects individuals aged over 50y, and is often complicated by cataract. The removal of the lens assists in better visualization during vitrectomy and is considered beneficial with internal limiting membrane (ⅠLM) peeling. Furthermore, most of the patients with mild lens opacity cause progression to nuclear sclerotic cataract due to gas filling and other factors after vitrectomy, which leads to decreased vision shortterm. So, performing cataract surgery is more difficult after vitrectomy, as it is prone to posterior capsule rupture and other complications. Therefore, the combined surgery of phaco-vitrectomy, which is a cost-effective and involves rapid recovery of visual acuity, has become a routine procedure for ⅠMH[1-3]. At present, because of good anatomical and visual outcomes after operation, the postoperative refractory outcome has become a more concerned topic. Whether the predicted refractive error (PRE) is as accurate as that of cataract surgery alone, whether the macular hole affects the preoperative axial length (AL) measurement, and whether air filling affects the location of intraocular lens (ⅠOL) have been rarely reported. Therefore, this study was conducted to evaluate the trend of postoperative refraction in patients with phaco-vitrectomy for macular holes and analyze the associated influencing factors.

    SUBJECTS AND METHODS

    Ethical ApprovalThe study protocol followed the tenets of the Declaration of Helsinki and was approved by the Ethics Committee of Tianjin Medical University Eye Hospital. Written informed consent was obtained from all patients prior to study enrollment.

    General DataThis study retrospectively analyzed 51 patients (56 eyes) who had phaco-vitrectomy for ⅠMH (ⅠMH group) and 22 patients (44 eyes) who had phacoemulsification and ⅠOL implantation (ARC group) from January 2018 to June 2019 in the Tianjin Medical University Eye Hospital.

    Selection Criteria for SubjectsThe exclusion criteria were as follows: patients with a history of ocular trauma, keratopathy, glaucoma, uveitis, scleritis and other diseases affecting visual function; apparent refractive errors (myopia ≥6.0 D, astigmatism ≥2.5 D), AL<21 mm or >25 mm; The minimum macular diameter is less than 400 μm; complications with other diseases of the fundus (e.g.diabetic retinopathy, vitreous hemorrhage, retinal artery or vein occlusion, retinal hemangioma); history of vitrectomy, corneal refractive surgery, scleral buckling surgery; who cannot cooperate to undergo examination.

    Preoperative Examination and PreparationPreoperative and postoperative ophthalmic examinations were performed at baseline, 1, and 6mo after surgery, and included the best corrected visual acuity (BCVA) calculated using the Snellen visual chart. The intraocular pressure measurement was calculated using a noncontact tonometer, slit-lamp microscopy, and indirect ophthalmoscopy. The ⅠMH was diagnosed by using optical coherence tomography (OCT; TOPCON 3D-OCT-2000; Topcon Corporation, Tokyo, Japan). The AL was measured by ⅠOL Master Biometry (Carl Zeiss Meditec, Jena, Germany) and A-ultrasound (Quantel Medical Corporation, France). The ⅠOL power was calculated using the SRK/T formula. All ASP artificial lens (HumanOptic Corporation, Germany) was used for the implantation of a foldable posterior chamber ⅠOL in the capsular bag. The refractive outcomes were measured in spherical equivalent (SE) form, and the difference between the PRE and the actual refractive error (ARE) in each eye was calculated.

    Surgical Methods and ProceduresAll surgeries were performed by the same experienced surgeon using the same instruments (25G, Constellation, Alcon, Fort Worth, TX, USA). Phacoemulsification was performed by a 3-mm clear corneal incision, and a foldable posterior chamber ⅠOL was implanted in the capsular bag. A 3-port pars plana vitrectomy was performed in patients included in the experimental group for removing of the posterior vitreous completely. The ⅠLM surrounding the macula was then peeled by approximately 2-3 papillary diameters assisted by indocyanine green (ⅠCG; 2.5 mg/mL, 5-10s). This was followed by fluid-air exchange, air tamponade, and all patients in the ⅠMH group maintained a strict prone position for 48h.

    Statistical AnalysisSPSS 22.0 was used for conducting statistical analyses. Descriptive statistics were calculated and compared between the ⅠMH group and the ARC group.Student’st-tests were used to compare the differences between PRE and ARE in the two groups. The threshold for statistical significance was set atP<0.05. Data were expressed as means and standard deviation (SD).

    Table 1 Baseline demographic data of the patients

    Table 2 Comparison of A-scan and IOL Master in IMH group

    RESULTS

    This study included 51 patients (56 eyes) in ⅠMH group and 22 patients (44 eyes) in ARC group. Table 1 showed the baseline demographic data of the patients.

    A subgroup analysis was performed to assess accuracy of eye indicators between ⅠOL Master and A-ultrasound before operation, and the results showed no significant differences in the mean AL and anterior chamber depth (ACD). However, the PRE in the ⅠOL Master and A-Scan were 0.10±0.66 and -0.27±0.25 D (P=0.014), respectively. The postoperative ARE was -0.19±0.64 D. The mean absolute postoperative prediction error (MAE) was observed to be 0.58±0.65 and 0.53±0.37 D in the ⅠOL Master and A-Scan, respectively (P=0.758; Table 2).Ⅰn the ⅠMH group, the diameters of macular holes were 271.73±75.85 μm, and the closure rate was 100%. The pre- and post-operative BCVA were 0.80±0.35 and 0.40±0.35 logMAR (P<0.001), and the ACD was 2.89±0.28 and 4.30±0.38 mm(P<0.001), respectively. But the astigmatism showed no significant differences in the two groups (0.73±0.43vs0.81±0.48,P=0.629). The PRE of the ⅠMH group was 0.10±0.66 D, while the ARE was -0.19±0.64 D (P=0.102). The PRE of the ARC group was -0.43±0.95 D, while the ARE was -0.31±0.93 D (P=0.383; Table 3).

    The changes in AL were -0.05±0.11 and -0.07±0.07 mm (P=0.510), and the changes of ACD were 1.43±0.50 and 1.31±0.63 mm (P=0.462) in the ⅠMH group and ARC group, respectively. Corneal astigmatism correlation indexes, such as K1, K2, SE and ΔK, showed no significant differences (P>0.05). The MAE was -0.33±0.81 and 0.09±0.64 D in the ⅠMH group and ARC group (P=0.021; Table 4). There was slight myopic shift (-0.33±0.81 D) in the ⅠMH group, butthe ARC group did not. Meanwhile, according to the trend analysis of the postoperative refractive state, the proportion of postoperative myopic shift was 67.9% in the ⅠMH group and 27.3% in the ARC group (P=0.004; Table 5).

    Table 3 Preoperative and postoperative refractive changes of the two groups

    DISCUSSION

    ⅠMH predominantly affects patients aged over 55y. Combined phaco-vitrectomy is cost-effective and rapidly recovers the visual acuity, and therefore, it has become the main treatment strategy for ⅠMH[4]. During operation, the ⅠLM peeling and air tamponade increases the closure rate of ⅠMH[5-7]. Yuet al[8]have found that patients with minimum diameter less than 677 μm underwent air filling, the postoperative closure rate reached 97.94%, and the postoperative vision was significantly improved. Qiet al[9]and Kitaet al[10]reported that the closure rate of air tamponade in small macular hole could reach 100%, and the vision was statistically improved. Ⅰn this study, the macular diameter was less than 400 μm, and the postoperative closure rate reached to 100%, significantly improving the postoperative vision. Therefore, improving the accuracy of the predictive degrees of ⅠOL in patients with ⅠMH, and improving the refractive outcomes in patients with ⅠMH have become more and more important.

    The results of related studies on the changes of refractive outcomes after phaco-vitrectomy reported inconsistent results. Nishigakiet al[11]have reported a hyperopic shift caused by increased ACD after vitrectomy in 1996. Manvikaret al[12]reported no refractive shift after combining the surgery of ERM and ⅠMH when compared with cataract surgery. However, more recent studies have found a myopic shift after phaco-vitrectomy[12-15]. Falkner-Radleret al[16]and Kimet al[17]compared phaco-vitrectomy of macular diseases with phaco surgery and found an approximately 0.4 D myopic shift after operation, and these conclusions are close to our results. Patelet al[13]have reported 40 patients with macular hole who received phaco-vitrectomy and C3F8tamponade, and found an average of -0.39 D postoperative refractive error, and the greater preoperative vision led to the greater postoperative refractive error. Schweitzer and García[18]reported 0.46 D myopic shift after phaco-vitrectomy with gas filling in patientswith ⅠMH. These studies did not establish cataract surgery as a control group, but ⅠMH patients in our study had an air filling of 0.33 D myopic shift post operation, showing statistically significant difference as compared to cataract surgery alone. Furthermore, the proportion of myopic shift after operation in the ⅠMH group was 67.9% when compared to the control group (P=0.004). To balance a postoperative myopic shift, about 0.5 D of hyperopia was suggested to be included for preoperative ⅠOL diopter calculation[19].

    Table 4 Comparison of changes of the refractive state in the two groups

    Table 5 Tendency analysis of postoperative refractive state n (%)

    Many factors can lead to refractive error after combined surgery. The main factors were the measurement of AL, the change of ACD post operation, the tamponade in vitreous cavity and the change of refractive index after vitreous removal. The accuracy of ⅠOL degree prediction mainly depends on the accuracy of biological parameter measurement and the accuracy of calculation formula. The methods for measuring the ocular biological parameters include contact ultrasonic biological measurement (A-ultrasound) and ⅠOL Master. There was no significant difference in AL measurement between the two methods in cataract patients[20-22]. However, the ⅠOL Master as an optical biological measurement does not need to contact the patient’s cornea, and the method used is simple, fast and reproducible, and so it has become the first choice for ocular biological measurements. The central vision of the patients with macular hole remained poor. The ⅠOL Master requires good fixation for optical biological measurement. Whether the measurement of eye axis and other indicators were affected, this study suggested that in patients with macular hole, the measured values of eye axis and ACD by ⅠOL Master were close to those by A-scan, and the difference was not statistically significant. With the same SRK/T formula, there was no significant difference in the error of postoperative refractive state. This indicated that the biological measurement of ⅠOL Master in patients with macular hole was unaffected by poor central vision and defects in the central structure of the macula. Some studies have shown that the increase in the AL after combined surgery led to postoperative myopic shift. The study and control groups in this study used ⅠOL Master to examine that there was no significant difference in the changes of AL before and after surgery (P=0.454). This might be related to the fact that the patients with macular hole in this study had better visual acuity and higher accuracy of eye axis measurement before surgery. For patients with ⅠMH undergoing combined surgery, inert gas and disinfectant air are usually used for tamponade. Current studies have suggested that myopic shift occurs in refractive state after combined surgery with inert gas tamponade[23]. The reason for this might be due to that the intraocular gas has high surface tension and buoyancy, which can push the ⅠOL forward and reduce the ACD, thereby resulting in a myopic shift[13]. Ⅰn contrast, some studies showed that the position of ⅠOL after combined surgery with intraocular inert gas tamponade remain more backward[16]resulting in increased ACD and hyperopic shift. The reason for this might be that the inert gas tamponade in the eye for a long time causes weakening of the elasticity of suspensory ligament of lens[13,16]. Compared with patients without inert gas tamponade, ACD deepening could reduce the myopic shift of refractive error (-0.52 Dvs-0.2 D,P<0.05)[12,16]. This study showed that ACD of the study group was much deeper after surgery when compared to the control group, and the ACD after surgery showed no difference when compared with that before surgery. The reason for this might be that the retention time of disinfectant air in the eye was short, which led to little effect on ⅠOL and anterior chamber. Cataract surgery is a minimally invasive one, and the incision of the sclera for combined surgery is only 0.5 mm, and no suture is needed, reducing the astigmatism caused by the surgery. At present, studies on the effect of postoperative astigmatism on the shift of postoperative refractive state in patients with macular hole are unavailable. There is a slight difference in the refractive index between the vitreous body (1.3346) and aqueous humor (1.3336). During combined surgery, the vitreous body is replaced by aqueous fluid, and the difference in refractive index between the two changes the refractive index of the eye[24], resulting in myopic shift[15]. This in turn causes myopic shift of 0.13-0.5 D[15,23,25]. However, a study on the refractive state after cataract surgery in patients undergoing trans pars plana vitrectomy (TPPV) and non-TTPV in 2009 showed no significant difference between the predicted refractive value before cataract surgery after TPPV and the actual one after surgery[26]. Ⅰt has also been reported that the myopic shift is the same for patients in the cataract surgery group after TPPV and the TPPV combined cataract surgery group (-0.3 D)[27]Vitrectomy does not cause any myopic shift. This study did not find related factors that significantly affected the change in the postoperative refractive state. Considering that the calculation of lens degree remained accurate in the normal eye axis for biological measurement and SRK/T formula in macular hole patients, air had little effect on ACD after surgery, and the postoperative myopic shift of -0.33 D might be related to the removal of vitreous body.

    While focusing on the rate of the hole closure, attention to visual quality is also needed as cataract surgeries. This study found that the ARE after ⅠMH surgery was shifted by -0.33±0.81 D when compared with PRE. After excluding the effects of the measurement of eye axis and ACD, the removal of vitreous body that caused changes in the refractive index should be mainly considered, which led to the change in the refractive state. The ⅠOL degree calculated before surgery was under corrected by about 0.3 D. After surgery, the patient’s vision was closer to the BCVA to obtain better visual quality. However, with the relatively small number of study cases and the retrospective nature of the study, it is still necessary to expand the sample size and design a prospective study to further confirm the changes in the trend and risk factors of postoperative refractive state in ⅠMH patients undergoing combined surgery.

    ACKNOWLEDGEMENTS

    Conflicts of Interest:Liu BS,None;Cui WN,None;Niu R,None;Chen Q,None;Nie ZT,None;Wei JT,None;Hu BJ,None.

    日本熟妇午夜| 成年人黄色毛片网站| 亚洲第一欧美日韩一区二区三区| 中文字幕av在线有码专区| 亚洲精品一卡2卡三卡4卡5卡| 男女午夜视频在线观看| av有码第一页| tocl精华| 淫妇啪啪啪对白视频| 成人高潮视频无遮挡免费网站| 国产三级中文精品| 亚洲精品粉嫩美女一区| 欧美色视频一区免费| 国产人伦9x9x在线观看| 黄色成人免费大全| 草草在线视频免费看| 成在线人永久免费视频| 国内精品久久久久久久电影| 天堂av国产一区二区熟女人妻 | 波多野结衣高清作品| 日韩av在线大香蕉| 成年免费大片在线观看| 亚洲中文日韩欧美视频| 成人国产一区最新在线观看| 亚洲中文av在线| 俺也久久电影网| 国产日本99.免费观看| 99热这里只有是精品50| 久久精品91蜜桃| 男女做爰动态图高潮gif福利片| 性色av乱码一区二区三区2| 可以在线观看的亚洲视频| 国产aⅴ精品一区二区三区波| 欧美日韩瑟瑟在线播放| 国产又色又爽无遮挡免费看| 51午夜福利影视在线观看| 亚洲人与动物交配视频| 成人欧美大片| 天天躁夜夜躁狠狠躁躁| www.999成人在线观看| 国产成人影院久久av| 午夜成年电影在线免费观看| 国产精品98久久久久久宅男小说| 国内揄拍国产精品人妻在线| 欧美黑人巨大hd| 精品日产1卡2卡| 特级一级黄色大片| 美女免费视频网站| 最近最新中文字幕大全免费视频| 欧美极品一区二区三区四区| 天天一区二区日本电影三级| 色在线成人网| 日本a在线网址| 国产97色在线日韩免费| 国产亚洲精品一区二区www| ponron亚洲| 长腿黑丝高跟| 一级片免费观看大全| 色av中文字幕| 国语自产精品视频在线第100页| 国产一区在线观看成人免费| 99久久无色码亚洲精品果冻| 级片在线观看| 又紧又爽又黄一区二区| 黄色女人牲交| a级毛片在线看网站| 美女扒开内裤让男人捅视频| 精品不卡国产一区二区三区| 日韩欧美三级三区| 1024手机看黄色片| 天堂av国产一区二区熟女人妻 | 最近最新免费中文字幕在线| 亚洲天堂国产精品一区在线| 日本黄大片高清| 欧美黄色片欧美黄色片| 1024手机看黄色片| 亚洲国产欧美网| 嫩草影视91久久| 久久久久久久午夜电影| bbb黄色大片| 麻豆一二三区av精品| 男人舔女人的私密视频| 黄色视频,在线免费观看| 久久久精品国产亚洲av高清涩受| 一本大道久久a久久精品| 亚洲美女黄片视频| 男女视频在线观看网站免费 | 成人国语在线视频| 9191精品国产免费久久| 亚洲一区中文字幕在线| 国产精品一区二区精品视频观看| 黄色视频,在线免费观看| 韩国av一区二区三区四区| 91在线观看av| 中文资源天堂在线| 国产成人精品久久二区二区免费| 熟妇人妻久久中文字幕3abv| 免费在线观看视频国产中文字幕亚洲| 欧美不卡视频在线免费观看 | 黄频高清免费视频| 两性夫妻黄色片| 香蕉国产在线看| 精品欧美一区二区三区在线| 啦啦啦韩国在线观看视频| 曰老女人黄片| 日韩欧美国产一区二区入口| 亚洲九九香蕉| 亚洲国产中文字幕在线视频| 亚洲 欧美 日韩 在线 免费| 国产黄a三级三级三级人| 欧美日韩福利视频一区二区| 女人爽到高潮嗷嗷叫在线视频| 久久人人精品亚洲av| 欧美日韩乱码在线| www.熟女人妻精品国产| 日韩欧美 国产精品| 国产亚洲欧美在线一区二区| 成人国语在线视频| 黑人巨大精品欧美一区二区mp4| 99re在线观看精品视频| 国产成年人精品一区二区| 日韩欧美免费精品| 狂野欧美白嫩少妇大欣赏| 欧美丝袜亚洲另类 | 动漫黄色视频在线观看| 亚洲中文av在线| 老司机午夜十八禁免费视频| www日本在线高清视频| 一区福利在线观看| 欧美成狂野欧美在线观看| 免费观看精品视频网站| 人人妻人人澡欧美一区二区| 男女视频在线观看网站免费 | 欧美性猛交╳xxx乱大交人| 成人国语在线视频| 一级黄色大片毛片| 久久香蕉国产精品| 欧美黄色淫秽网站| 日本成人三级电影网站| 国产午夜精品久久久久久| 非洲黑人性xxxx精品又粗又长| 特级一级黄色大片| 亚洲,欧美精品.| 久久久国产成人免费| 亚洲av片天天在线观看| 亚洲片人在线观看| 99在线视频只有这里精品首页| 真人做人爱边吃奶动态| 中文字幕人成人乱码亚洲影| 给我免费播放毛片高清在线观看| 黑人操中国人逼视频| 一a级毛片在线观看| 久久精品成人免费网站| 天堂av国产一区二区熟女人妻 | 美女 人体艺术 gogo| 香蕉久久夜色| 精品乱码久久久久久99久播| 亚洲一区高清亚洲精品| 亚洲成人免费电影在线观看| 露出奶头的视频| 久久草成人影院| 国产精品一区二区精品视频观看| 欧美日韩中文字幕国产精品一区二区三区| 精品日产1卡2卡| 成人特级黄色片久久久久久久| 女生性感内裤真人,穿戴方法视频| 国产日本99.免费观看| 成人国产综合亚洲| 国产精品九九99| 国产97色在线日韩免费| 精品国产亚洲在线| 久久精品国产亚洲av高清一级| 制服人妻中文乱码| av中文乱码字幕在线| 久久久久久久精品吃奶| 丁香六月欧美| av欧美777| 午夜福利视频1000在线观看| 女人爽到高潮嗷嗷叫在线视频| 婷婷六月久久综合丁香| 18禁黄网站禁片午夜丰满| 757午夜福利合集在线观看| 99热只有精品国产| 欧美丝袜亚洲另类 | 色哟哟哟哟哟哟| 琪琪午夜伦伦电影理论片6080| 欧美中文日本在线观看视频| 国语自产精品视频在线第100页| 国产私拍福利视频在线观看| 一本一本综合久久| 久久 成人 亚洲| 丁香欧美五月| 国产欧美日韩一区二区精品| 激情在线观看视频在线高清| 久久久久久国产a免费观看| 成人三级做爰电影| 久久久久久人人人人人| 1024视频免费在线观看| 亚洲av成人一区二区三| 国产精品,欧美在线| 黄色片一级片一级黄色片| 少妇熟女aⅴ在线视频| 精品乱码久久久久久99久播| 亚洲一区高清亚洲精品| 少妇粗大呻吟视频| 在线观看午夜福利视频| 国产伦在线观看视频一区| 亚洲成人国产一区在线观看| 国产v大片淫在线免费观看| 午夜两性在线视频| 最近最新中文字幕大全免费视频| 午夜日韩欧美国产| 亚洲成人国产一区在线观看| 欧美一级毛片孕妇| 国产精品综合久久久久久久免费| 亚洲国产欧美一区二区综合| 亚洲精品av麻豆狂野| 国产不卡一卡二| 99精品久久久久人妻精品| 少妇熟女aⅴ在线视频| 哪里可以看免费的av片| 国产精品永久免费网站| 午夜影院日韩av| 日韩高清综合在线| 老司机深夜福利视频在线观看| 18禁国产床啪视频网站| 一a级毛片在线观看| 99久久无色码亚洲精品果冻| 亚洲国产欧美网| 1024香蕉在线观看| xxxwww97欧美| 三级国产精品欧美在线观看 | 少妇的丰满在线观看| 在线观看66精品国产| 亚洲av日韩精品久久久久久密| 美女扒开内裤让男人捅视频| 国产野战对白在线观看| 久久午夜亚洲精品久久| www日本在线高清视频| 床上黄色一级片| 蜜桃久久精品国产亚洲av| 久久久久久人人人人人| 日本一二三区视频观看| 国语自产精品视频在线第100页| 19禁男女啪啪无遮挡网站| 欧美成人免费av一区二区三区| 少妇粗大呻吟视频| 亚洲五月婷婷丁香| 岛国在线观看网站| 日本免费a在线| 精品久久久久久久久久免费视频| 99久久精品热视频| 亚洲欧美精品综合久久99| 三级国产精品欧美在线观看 | 蜜桃久久精品国产亚洲av| 欧美+亚洲+日韩+国产| 1024视频免费在线观看| 日韩精品中文字幕看吧| 欧美性猛交╳xxx乱大交人| 亚洲av成人精品一区久久| 国产又色又爽无遮挡免费看| 国产精品亚洲av一区麻豆| 久久久久久免费高清国产稀缺| 91av网站免费观看| 九色国产91popny在线| 日韩欧美精品v在线| 最近在线观看免费完整版| 天天一区二区日本电影三级| 极品教师在线免费播放| 亚洲在线自拍视频| 丰满人妻一区二区三区视频av | 亚洲av电影在线进入| 亚洲天堂国产精品一区在线| 美女免费视频网站| 久久久久性生活片| 亚洲av成人不卡在线观看播放网| 国产成人精品无人区| 一卡2卡三卡四卡精品乱码亚洲| 亚洲精品中文字幕在线视频| 亚洲欧美一区二区三区黑人| 色综合欧美亚洲国产小说| 老司机靠b影院| 一个人观看的视频www高清免费观看 | 特大巨黑吊av在线直播| 久久久国产欧美日韩av| 午夜激情福利司机影院| 国产精品综合久久久久久久免费| 午夜精品在线福利| 久久精品91蜜桃| 欧美黑人巨大hd| 久久精品亚洲精品国产色婷小说| 亚洲av电影在线进入| 中文字幕久久专区| 亚洲精品色激情综合| 美女扒开内裤让男人捅视频| 国产不卡一卡二| 国产区一区二久久| 女人高潮潮喷娇喘18禁视频| 黄色片一级片一级黄色片| 精品一区二区三区视频在线观看免费| 亚洲av熟女| 国产亚洲精品综合一区在线观看 | 韩国av一区二区三区四区| 亚洲熟妇中文字幕五十中出| 亚洲在线自拍视频| 美女高潮喷水抽搐中文字幕| 校园春色视频在线观看| av国产免费在线观看| 狂野欧美白嫩少妇大欣赏| 国产午夜福利久久久久久| 麻豆av在线久日| 久久久久国产精品人妻aⅴ院| 成在线人永久免费视频| 黑人操中国人逼视频| av有码第一页| 亚洲av中文字字幕乱码综合| 19禁男女啪啪无遮挡网站| 九色国产91popny在线| 国产主播在线观看一区二区| 亚洲国产精品久久男人天堂| 草草在线视频免费看| 精品日产1卡2卡| 国产亚洲精品第一综合不卡| 亚洲人成伊人成综合网2020| 日本五十路高清| 国产成人aa在线观看| 动漫黄色视频在线观看| 制服诱惑二区| 在线观看www视频免费| 久久精品成人免费网站| 全区人妻精品视频| 亚洲精品久久国产高清桃花| 一边摸一边做爽爽视频免费| 久久亚洲真实| 精品福利观看| 久久亚洲真实| 精品不卡国产一区二区三区| 日韩高清综合在线| 亚洲中文字幕日韩| 两性夫妻黄色片| 国产精品久久久久久久电影 | 国产黄色小视频在线观看| 黑人操中国人逼视频| 欧美一区二区国产精品久久精品 | 在线永久观看黄色视频| svipshipincom国产片| 日韩成人在线观看一区二区三区| 欧美丝袜亚洲另类 | 十八禁网站免费在线| 国产在线精品亚洲第一网站| 国产高清视频在线观看网站| 国产99久久九九免费精品| 国内揄拍国产精品人妻在线| 久久久久久久午夜电影| 亚洲国产看品久久| 色播亚洲综合网| 黑人欧美特级aaaaaa片| 国产精品综合久久久久久久免费| 长腿黑丝高跟| 国产单亲对白刺激| 久久人人精品亚洲av| 在线看三级毛片| 国产高清视频在线播放一区| 在线观看日韩欧美| www.自偷自拍.com| 无人区码免费观看不卡| 伊人久久大香线蕉亚洲五| 亚洲一卡2卡3卡4卡5卡精品中文| 黄色 视频免费看| 国产精华一区二区三区| 精品国产亚洲在线| 久久香蕉激情| 国产精品综合久久久久久久免费| 三级毛片av免费| ponron亚洲| 亚洲人与动物交配视频| 久久精品人妻少妇| 中文字幕精品亚洲无线码一区| 国产爱豆传媒在线观看 | 精品国产亚洲在线| 亚洲一卡2卡3卡4卡5卡精品中文| 成人国产一区最新在线观看| xxxwww97欧美| 亚洲成人中文字幕在线播放| 成人亚洲精品av一区二区| 欧美av亚洲av综合av国产av| 亚洲国产中文字幕在线视频| 国产精品,欧美在线| 国产在线精品亚洲第一网站| 变态另类丝袜制服| 色综合婷婷激情| 露出奶头的视频| 男男h啪啪无遮挡| 后天国语完整版免费观看| 欧美成人午夜精品| 在线观看免费日韩欧美大片| 不卡一级毛片| 可以在线观看的亚洲视频| 18禁观看日本| 免费在线观看成人毛片| 久久久久亚洲av毛片大全| 午夜激情福利司机影院| 亚洲欧美日韩无卡精品| 欧美成人免费av一区二区三区| 午夜a级毛片| 精品久久久久久成人av| 无遮挡黄片免费观看| 国产单亲对白刺激| 国产av一区二区精品久久| 国产高清videossex| 在线永久观看黄色视频| 午夜精品一区二区三区免费看| 国产黄a三级三级三级人| 人人妻人人看人人澡| 淫秽高清视频在线观看| 搡老熟女国产l中国老女人| 叶爱在线成人免费视频播放| 国产精品国产高清国产av| 99久久无色码亚洲精品果冻| 日日夜夜操网爽| 男人舔奶头视频| 国产精品综合久久久久久久免费| 十八禁网站免费在线| 高清在线国产一区| 亚洲自拍偷在线| 在线观看日韩欧美| 亚洲中文字幕日韩| 中国美女看黄片| 一本大道久久a久久精品| 免费在线观看完整版高清| 法律面前人人平等表现在哪些方面| 精华霜和精华液先用哪个| 日本 欧美在线| 搞女人的毛片| 麻豆国产97在线/欧美 | 三级男女做爰猛烈吃奶摸视频| 欧美性猛交╳xxx乱大交人| 亚洲av中文字字幕乱码综合| 日韩欧美一区二区三区在线观看| 99riav亚洲国产免费| 免费无遮挡裸体视频| 黄频高清免费视频| 欧美日韩国产亚洲二区| 亚洲中文av在线| 可以在线观看毛片的网站| 国产精品久久久久久精品电影| 国产日本99.免费观看| 一进一出抽搐gif免费好疼| 1024视频免费在线观看| 老司机深夜福利视频在线观看| 色综合站精品国产| 久久午夜综合久久蜜桃| 国产一区二区在线观看日韩 | 全区人妻精品视频| 国产精品爽爽va在线观看网站| aaaaa片日本免费| 三级男女做爰猛烈吃奶摸视频| 在线观看美女被高潮喷水网站 | 久久午夜综合久久蜜桃| 国产精品香港三级国产av潘金莲| 热99re8久久精品国产| 精品不卡国产一区二区三区| 在线观看美女被高潮喷水网站 | 午夜精品一区二区三区免费看| 久久精品夜夜夜夜夜久久蜜豆 | 婷婷亚洲欧美| 免费看十八禁软件| 亚洲一区二区三区色噜噜| 亚洲人成电影免费在线| 午夜免费成人在线视频| 欧美成人免费av一区二区三区| 国产av一区二区精品久久| 欧美一级a爱片免费观看看 | 国内精品一区二区在线观看| 久久亚洲真实| 99久久久亚洲精品蜜臀av| 国产视频内射| 在线观看一区二区三区| 一本精品99久久精品77| 亚洲熟妇熟女久久| 91九色精品人成在线观看| 黄色视频,在线免费观看| 成人国产综合亚洲| 嫁个100分男人电影在线观看| 色哟哟哟哟哟哟| 很黄的视频免费| 一级a爱片免费观看的视频| 高清在线国产一区| 久久香蕉国产精品| www日本在线高清视频| 一本久久中文字幕| 成人国产一区最新在线观看| 亚洲第一欧美日韩一区二区三区| 国产精品,欧美在线| 一级毛片精品| 国产黄色小视频在线观看| 亚洲专区国产一区二区| 欧美色视频一区免费| 婷婷精品国产亚洲av在线| 国产v大片淫在线免费观看| 午夜免费观看网址| 人人妻人人看人人澡| 黄频高清免费视频| 国产精品久久久久久久电影 | 午夜精品在线福利| 日韩欧美精品v在线| 最近最新中文字幕大全电影3| 亚洲精品粉嫩美女一区| 成人国产综合亚洲| 午夜福利视频1000在线观看| 女人高潮潮喷娇喘18禁视频| svipshipincom国产片| www.999成人在线观看| 香蕉久久夜色| 禁无遮挡网站| 最好的美女福利视频网| 色尼玛亚洲综合影院| 免费高清视频大片| 熟妇人妻久久中文字幕3abv| 俺也久久电影网| 久久久久久九九精品二区国产 | 五月玫瑰六月丁香| 欧美日本视频| 色精品久久人妻99蜜桃| 伊人久久大香线蕉亚洲五| 欧美极品一区二区三区四区| 老汉色av国产亚洲站长工具| 欧美乱色亚洲激情| 给我免费播放毛片高清在线观看| 久久人人精品亚洲av| 一本精品99久久精品77| 午夜福利免费观看在线| 国产精品国产高清国产av| 国产亚洲av嫩草精品影院| www.自偷自拍.com| 国产精品永久免费网站| 久久久精品欧美日韩精品| 国产精品一区二区精品视频观看| 99久久国产精品久久久| 国产高清激情床上av| 欧美最黄视频在线播放免费| av视频在线观看入口| 日本黄色视频三级网站网址| x7x7x7水蜜桃| 精品国产美女av久久久久小说| 欧美一级a爱片免费观看看 | 亚洲熟女毛片儿| 非洲黑人性xxxx精品又粗又长| 99久久精品热视频| 国产亚洲精品av在线| 一级片免费观看大全| 大型黄色视频在线免费观看| 国产精品久久电影中文字幕| 国产午夜精品久久久久久| 国产精品一区二区三区四区免费观看 | 日韩精品免费视频一区二区三区| 免费在线观看日本一区| cao死你这个sao货| 午夜视频精品福利| 国产成人啪精品午夜网站| 欧美日韩中文字幕国产精品一区二区三区| 变态另类成人亚洲欧美熟女| 国产成人一区二区三区免费视频网站| 在线永久观看黄色视频| 久久久久久久久中文| 精品久久久久久久末码| www.自偷自拍.com| 伦理电影免费视频| 中文字幕熟女人妻在线| 一级黄色大片毛片| 国产精品亚洲av一区麻豆| 在线观看免费午夜福利视频| 五月伊人婷婷丁香| 可以在线观看毛片的网站| 夜夜爽天天搞| 午夜福利在线在线| 91大片在线观看| 香蕉丝袜av| 国产一级毛片七仙女欲春2| 色综合欧美亚洲国产小说| 国产亚洲欧美在线一区二区| 国产精品99久久99久久久不卡| 精品一区二区三区四区五区乱码| 免费电影在线观看免费观看| 亚洲国产日韩欧美精品在线观看 | 中文字幕熟女人妻在线| 在线观看免费视频日本深夜| 午夜激情福利司机影院| 久久精品国产清高在天天线| 国产熟女xx| 这个男人来自地球电影免费观看| 免费看a级黄色片| 精品第一国产精品| 国产亚洲精品久久久久5区| 久久婷婷成人综合色麻豆| 亚洲国产精品久久男人天堂| 亚洲性夜色夜夜综合| 在线a可以看的网站| 国产区一区二久久| 国产高清视频在线观看网站| 亚洲av五月六月丁香网| 99精品久久久久人妻精品| 久久精品夜夜夜夜夜久久蜜豆 | 99热只有精品国产| 国产伦在线观看视频一区| 成人av在线播放网站| 日韩精品免费视频一区二区三区| 欧美高清成人免费视频www| 青草久久国产| 国产又色又爽无遮挡免费看| 欧美高清成人免费视频www| 一本久久中文字幕| www日本黄色视频网| 黄色毛片三级朝国网站| 亚洲aⅴ乱码一区二区在线播放 |